ISTANBUL MEDIPOL UNIVERSITY Course Learning Outcomes of

ISTANBUL MEDIPOL UNIVERSITY
Course Learning Outcomes of MEDICAL BIOLOGY and GENETICS
Course Code and Title
BES111050, ÇGL111050-MEDICAL BIOLOGY and GENETICS
Department / Programme
Faculty of Science /Nutrition and Dietetics/Child Development
Language of Education
Turkish
Course Type
Compulsory
Lecturer(s)
Lect. Dr. Mavi Deniz Özel
Office Hours
Wednesday 13.30- 16.15
Course Objective
The aim of this course is to explain structure and function of cells and genetic material, in addition to
inform about genetic mechanisms.
1. The students will be able to define cell types, organelles, genetic material.
1.1. They describe functions of organelles and cell membrane and explain cell skeleton.
1.2. They describe chromosomes, DNA and RNA.
1.3. They describe organization of genes and regulation of gene expression.
2. The students will be able to explain the stages of cell cycle and cell divisions and also debate cellular
2.1. They describe stages and check points of cell cycle.
2.2. They explain mitotic and meiotic divisions and associate them with genetic abnormalities and cancer.
2.3. They describe transcription and regulation.
2.4. They describe translation and regulation.
Learning Outcomes and
Subordinate Skills
3. The students will be able to categorize chromosomal abnormalities and DNA damage mechanisms and
associate them with diseases.
3.1. They describe numeric and structural chromosomal abnormalities, associate them with diseases.
3.2. They explain DNA mutations and repair mechanisms.
3.3. They explain cell aging, apoptosis and development of cancer.
4. The students will able to identify inheritance patterns and discuss the application areas of molecular
biology and genetic diagnosis techniques.
4.1. They describe Mendelian inheritance.
4.2. They describe non-Mendelian inheritance.
4.3. They explain human genomne project.
4.4. They explain molecular biology techniques and associate them with genetic diagnosis.
Generic Competences
Productive, investigative, creative, questioning, environmental awareness, effective use of mother
language, critical thinking.
Week
Topics
1. Introduction to medical biology, cell and cell examination methods
2. Cellular organization, cell membrane
3. Cell skeleton and organelles
4. Structure and function of genetic material, DNA, RNA, organization of genes and regulation of gene
expression
5. Chromatin, chromosome, centromere and telomere
6. Cell cycle and DNA Replication
7. Transcription and translation
8.
Chromosome abnormalities, mutation and polymorphism
9. DNA damage and repair mechanisms
10. Cellular aging, apoptosis and molecular mechanisms of cancer
11. Mendelian and non-Mendelian inheritance
12. Human genome project
13. Molecular biology techniques
14. Cytogenetics, prenatal diagnosis and genetic counseling
Outline
Instructional Methods and
Techniques
Lecture, demonstration, illustration and brain storming.
Course Requirements
Students have to attend classes regularly, participate in discussions, prepare assignment and deliver it on
time.
Textbook
1)Lecturer's presentations
2)Tıbbi Biyoloji Ders Kitabı, Cerrahpaşa Tıp Fakültesi Yayın No:275, İstanbul, 2009.
3)Prof. Dr. Hasan Veysi Güneş, Moleküler Hücre Biyolojisi, İstanbul Tıp Kitabevi, 3. Baskı, 2013.
4)Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, Martin Raff, Keith
Roberts, Peter
Walter. Essential Cell Biology, Fourth Edition, Garland Science Publishers, USA, 2013.
5)Robert L. Nussbaum, Roderick R. Mcinnes, Huntington F. Willard. Thompson and Thompson Tıbbi
Genetik,
Güneş tıp Kitabevi, 2005.
Suggested
1)Alberts B, Bray A, Lewis J. Molecular Biology of Cell, Garland Publishing, Inc., New York 1989.
References
Suggested
Sources
Hours
1)Alberts B, Bray A, Lewis J. Molecular Biology of Cell, Garland Publishing, Inc., New York 1989.
2)David L. Nelson, Michael M. Cox, Lehninger Biyokimyanın İlkeleri, Palme Yayınevi, Ankara, 2013
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